See Also:

pyritous (iou) and bcl (medicine)


pyritous (iou)



pyritous adjective. M18.
[from PYRITES + -OUS.]
Geology. Of or pertaining to pyrites; of the Nature of or containing pyrites.
Also pyritose adjective (now rare) M18.

bcl (medicine)


bcl
<oncogene> Two variants of this oncogene are recognised.

1. Bcl-2: A proto-oncogene, activated by chromosome translocation in human B-cell lymphomas (hence bcl). Encodes a plasma membrane protein. The gene product inhibits programmed cell death (apoptosis) and is homologous with the worm gene ced 9.

See: ced mutant.

2. Bcl-3: An oncogene associated with some cases of B-cell chronic lymphocytic leukaemias. The protein product contains seven ankyrin repeats very similar to those found in I kappa B. Seems to interfere with binding of 50 kD subunit of NF kappa B to DNA.