See Also: 2-isopropylmalate synthase(medicine)
isopropylmalate isomerase(medicine)
3-isopropylmalate dehydrogenase(medicine)
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2-isopropylmalate synthase (medicine)


2-isopropylmalate synthase
<enzyme> An enzyme that catalyses the first step in the biosynthetic pathway to leucine, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid.

Chemical name: 3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)

Registry number: EC 4.1.3.12