See Also: 2-ketoadipic acid(medicine)
alpha-amino-beta-ketoadipic acid(medicine)
2-ketoadipic acidemia(medicine)
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Rambourg's chromic acid-phosphotungstic acid stain(medicine)
medicine man(encyclopedia)
medicine(dictionary)
medicine(encyclopedia)

2-ketoadipic acid (medicine)


2-ketoadipic acid


HOOCCH2CH2CH2COCOOH;an intermediate in l-tryptophan and l-lysine catabolism; 2-ketoadipic acid accumulates in certain inherited disorders, probably due to a deficiency of one of the proteins in the alpha-ketoadipate dehydrogenase complex.

2-ketoadipic acid dehydrogenase complex, the multienzyme complex that reacts 2-ketoadipic acid with coenzyme A and NAD+ to produce glutaryl-CoA, CO2, and NADH + H+ in l-lysine and l-tryptophan catabolism; a deficiency of one of the proteins in this complex results in 2-ketoadipic acidemia.