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5-oxoproline(medicine)
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4-oxoproline reductase (medicine)


4-oxoproline reductase -->
4-hydroxyproline oxidase


A flavoenzyme that catalyses the conversion of 4-hydroxyproline to d'-pyrroline-3-hydroxy-5-carboxylate using FAD; this enzyme appears to be deficient in individuals with hyperhydroxyprolinaemia, an enzyme that catalyses the reaction of 4-hydroxyproline with NAD+ to form NADH and 4-oxoproline.

Synonym: 4-oxoproline reductase.