See Also: Beta-hydroxy-beta-methylglutaryl-CoA(medicine)
3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase(medicine)
3-Hydroxy-3-methylglutaryl-CoA(medicine)
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase(medicine)
beta-1,3-galactosyl-0-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase(medicine)
beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase(medicine)
UDP-GalNAc-beta-galactose beta 1,4-N-acetylgalactosaminyltransferase(medicine)
androst-5-ene-3 beta,17 beta-diol(medicine)
beta-n-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase(medicine)
5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase(medicine)

Beta-hydroxy-beta-methylglutaryl-CoA (medicine) and uncinaria (medicine)


Beta-hydroxy-beta-methylglutaryl-CoA (medicine)


beta-hydroxy-beta-methylglutaryl-CoA


-OOCCH2C(OH)(CH3)CH2COS-CoA;a key intermediate in the synthesis of ketone bodies and of steroids.

Synonym: 3-hydroxy-3-methylglutaryl-CoA.

Beta-hydroxy-beta-methylglutaryl-lyase, an enzyme, found primarily in liver and rumen epithelium that catalyses the formation of acetyl-CoA and acetoacetate from beta-hydroxy-beta-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis.

Beta-hydroxy-beta-methylglutaryl-reductase, an enzyme that catalyses the rate-limiting step of cholesterol biosynthesis, beta-hydroxy-beta-methylglutaryl-CoA + 2NADPH + 2H+ → mevalonate + 2NADP+ + coenzyme A.

Beta-hydroxy-beta-methylglutaryl-synthase, an enzyme in mitochondria that catalyses the reaction of acetyl-CoA with acetoacetyl-CoA and water to form beta-hydroxy-beta-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur.


uncinaria (medicine)


Uncinaria


A genus of nematode hookworms that infect various mammals. Species include Uncinaria stenocephala, the European hookworm of dogs, cats, and various wild carnivores, also found in North America, where it is much less common than Ancylostoma caninum, though it has been implicated in human cutaneous larva migrans.

Origin: LL. Uncinus, a hook