See Also: Canavan's disease(medicine)
Disease, Canavan(health)
Canavan disease(medicine)
Canavan disease(health)
Canavan-van Bogaert-Bertrand disease(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Canavan's sclerosis(medicine)
Canavan, Myrtelle(medicine)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
Orthomolecular medicine (orthomolecular nutritional medicine, orthomolecular therapy)(health)

Canavan's disease (medicine)


Canavan's disease
Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.

See: leukodystrophy.

Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.