See Also: Schilder's disease(dictionary)
Schilder's disease(medicine)
Flatau-Schilder disease(medicine)
schilder syndrome(medicine)
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Schilder's disease (medicine)


Schilder's disease
Term used to describe at least two separate disorders described by Schilder: 1) Diffuse sclerosis or encephalitis periaxialis diffusa; a nonfamilial disorder affecting primarily children and young adults and characterised by progressive dementia, visual disturbances, deafness, pseudobulbar palsy, and hemiplegia or quadriplegia. Most patients die within a few years of onset; pathologically, there is a large, asymmetrical area of myelin destruction, sometimes involving an entire cerebral hemisphere, and typically with extension across the corpus callosum. 2) The leukodystrophies.

Synonym: encephalitis periaxialis diffusa, Flatau-Schilder disease.