See Also: atebrine hydrochloride(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
Orthomolecular medicine (orthomolecular nutritional medicine, orthomolecular therapy)(health)
medicine(dictionary)
medicine(2)(dictionary)
medicine(1)(dictionary)
medicine man(dictionary)
medicine(encyclopedia)
medicine man(encyclopedia)

atebrine hydrochloride (medicine)


atebrine hydrochloride -->
quinacrine hydrochloride


An acridine derivative, C23H30ClN3O-2HCl-2H2O, used as an antimalarial that destroys the trophozoites of Plasmodium vivax and P. Falciparum, but does not affect the gametocytes, sporozoites, or exoerythrocytic stage of parasites; also used as an anthelmintic. As a dihydrochloride, it is used as a stain in cytogenetics to demonstrate Y chromatin by fluorescent microscopy. Quinacrine hydrochloride intercalates with DNA and also uncouples oxidative and photophosphorylation.

Synonym: atebrine hydrochloride, mepacrine hydrochloride.