See Also: direct Coombs' test(medicine)
Coombs' test(medicine)
indirect Coombs' test(medicine)
direct fluorescent antibody test(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Coombs, Robin(medicine)
Coombs murmur(medicine)
Coombs' serum(medicine)
coombs' reaction(medicine)
Coombs, Carey(medicine)

direct Coombs' test (medicine)


direct Coombs' test


A test for detecting sensitised erythrocytes in erythroblastosis foetalis and in cases of acquired immune haemolytic anaemia: the patient's erythrocytes are washed with saline to remove serum and unattached antibody protein, then incubated with Coombs' anti-human globulin (usually serum from a rabbit or goat previously immunised with human globulin); after incubation, the system is centrifuged and examined for agglutination, which indicates the presence of so-called incomplete or univalent antibodies on the surface of the erythrocytes.