See Also: bacteriophage lambda(medicine)
lambda bacteriophage(medicine)
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Lambda(money)
lambda(dictionary)
Lambda(medicine)
Lambda(finance)
lambda chain(medicine)
lambda sign(medicine)
lambda phage(medicine)

lambda bacteriophage (medicine)


lambda bacteriophage
<virology> Bacterial DNA virus, first isolated from E. Coli. Its structure is similar to that of the T even phages.

Lambda genetic material consists of a double-stranded DNA molecule with 5' twelve-base-pair sticky ends, known as cos sites, which permit circularisation of the DNA molecule. It shows a lytic cycle and a lysogenic cycle and studies on the control of these alternative cycles have been very important for our understanding of the regulation of gene transcription.

It is used as a cloning vector, accommodating fragments of DNA up to 15 kilobase pairs long. For larger pieces, the cosmid vector was constructed from its ends.