See Also: lupus coagulation inhibitor(medicine)
lipoprotein-associated coagulation inhibitor(medicine)
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Coagulation(medicine)
Coagulation(health)
coagulation(encyclopedia)
coagulation(dictionary)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
coagulation profile(medicine)
coagulation vitamin(medicine)

lupus coagulation inhibitor (medicine)


lupus coagulation inhibitor


An antiphospholipid antibody found in association with systemic lupus erythematosus (lupus erythematosus, systemic), antiphospholipid syndrome, and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including foetal death and spontaneous abortion, as well as a variety of haematologic and neurologic complications.