scleroderma, systemic (medicine) and tick(4) (iou)

scleroderma, systemic (medicine)

scleroderma, systemic

A chronic, progressive dermatosis characterised by boardlike hardening and immobility of the affected skin, with visceral involvement, especially of lungs, oesophagus, kidneys and heart. It may be accompanied by calcinosis, raynaud's phenomenon, and telangiectasis (crest syndrome). It includes acrosclerosis and sclerodactyly.

tick(4) (iou)

tick noun3. LME.
[Perh. rel. to Low German tikk touch, moment, instant, Dutch tik pat, touch, Middle High German zic slight touch from Germanic base. Cf. TIG noun1.]
a. A light but distinct touch; a light quick stroke or touch; a pat, a tap. obsolete exc. dial. LME.
b. = TAG noun2 1. E17.
A distinct quick light dry sound, as of the collision of two small metal bodies; esp. the regular slight click made by a watch or clock. L17.
b. A beat of the heart or pulse. rare. E19.
A small dash or Other mark (now usu. '') made with a pen or pencil to draw attention to something, to check off an item in a list, to indicate the correctness of a written answer or remark, etc. M19.
G. Gorer Questions..that..could be answered either with a simple tick or by Writing.
b. A small spot or speck of colour on the skin or coat of an animal. Scot. rare. L19.
c. A ticked item on a list, esp. of birds to be observed. L20.
Bird Watching Brian..recorded his first Willow Warbler, while two Oxfordshire regulars both claimed new ticks.
The time between two ticks of a clock; a moment, an instant. colloq. L19.
in two ticks in a very short time. on the tick, to the tick punctually, promptly.
E. W. Hornung I should have been spotted in a tick by a spy. E. Reveley Just wait a tick while I tell George where we'll be.
Stock Exchange. The smallest recognized amount by which a price (of a commodity, stock, etc.) may fluctuate. L20.

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