See Also: phase III clinical trial(medicine)
clinical trial, phase IV(medicine)
clinical trial, phase III(medicine)
clinical trial, phase II(medicine)
clinical trial, phase I(medicine)
phase II clinical trial(medicine)
phase I clinical trial(medicine)
Clinical trial(health)
clinical trial(medicine)
human clinical trial(medicine)

Coloration (money) and phase I clinical trial (medicine)


Coloration (money)


Definition: Deliberate distortion of information.







phase I clinical trial (medicine)


phase I clinical trial
<pharmacology> The earliest stage clinical trial for studying an experimental drug in humans. Phase I trials are generally comparatively small and are used to determine toxicity and maximum dose.

They provide an initial evaluation of a drug's safety and pharmacokinetics-how the drug is absorbed, what tissues it reaches and how long it takes to leave the body. Such studies also usually test various doses of the drug (dose-ranging) to obtain an indication of the appropriate dose to use in later studies.

The patients in these trials usually have advanced disease and have already received best available chemotherapy, therefore, seeing a repose is significant partially because this means there is a lack of cross-resistance between two anti-cancer drugs.